Focal adhesion 中文
WebFeb 15, 2024 · Focal adhesions play a key role in cell migration, by allowing the cell to move in response to chemical and mechanical signals from the ECM. When an integrin binds to a protein in the ECM, it triggers the formation of new focal adhesions at the leading edge of the cell, and the breakdown of focal adhesions at the trailing edge.This … WebAdhesion plaque focal adhesion, focal contact 黏著斑斑狀黏附; The correlation between expression of focal adhesion kinase and vascular endothelial growth factor in human rectal carcinoma 在直腸癌中的表達及其相互關系的研究; Inhibition of focal adhesion kinase induces the anoikis of cardiac fibroblasts with rna interference technique ...
Focal adhesion 中文
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Web黏着斑激酶(focal adhesion kinase, FAK)是一种胞质非受体酪氨酸激酶。. FAK和肿瘤密切相关,在多种癌细胞中高表达,促进癌细胞的发生、生长、存活、增殖、粘附、转移 … Web比较贴切的中文意思视规律的种类而定,这里指focal adhesion的“更新”,因为其处于动态的形成和解散过程中。还有很多用到turnover的地方,比如蛋白的turnover(合成和降解)。
WebJul 18, 2011 · Focal adhesion kinase (FAK) is a cytoplasmic tyrosine kinase that plays critical roles in integrin-mediated signal transductions and also participates in signaling by other cell surface receptors. In integrin-mediated cell adhesion, FAK is activated via disruption of an auto-inhibitory intra-molecular interaction between its amino terminal … WebIntegrin-dependent cell adhesions come in different shapes and serve in different cell types for tasks ranging from cell-adhesion, migration, and the remodeling of the extracellular matrix to the formation and stabilization of immunological and chemical synapses. A major challenge consists in the id …
WebOverexpression of focal adhesion kinase (FAK) has been well correlated with tumor development and/or the maintenance of tumor phenotype. In addition, inappropr 掌桥科研 一站式科研服务平台 WebNov 9, 2024 · A mechanosensing function of focal adhesions is manifested by rigidity-dependent adhesion assembly and turnover, which involves hundreds of different focal adhesion proteins that alter cell behavior during spreading and migration ().In addition, focal adhesion mechanosensing regulates pathways such as AKT, mitogen-activated …
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WebAug 23, 2016 · Focal adhesions are multi-protein assemblies containing integrins (shown in red) that connect the cell to the surrounding extracellular matrix (ECM). Talin and vinculin (shown in yellow and purple, respectively) link integrins to the actin cytoskeleton. Bouchet et al. report that a mechanically sensitive adaptor protein talin must interact with ... porsche boost buttonWebFocal adhesions are integrin-containing, multi-protein structures that form mechanical links between intracellular actin bundles and the extracellular substrate in many … porsche behind the scenesWebFocal adhesion associated proteins in detail The focal adhesion is a structural unit that additionally directs the flow of information from outside the cell to the inside. The cell processes the relayed information and reacts according to cues it receives from its constantly changing environment. Below is a brief summary of some of the most ... iris hornbachWebJan 1, 2024 · The focal adhesion turnover is also facilitated by calpain-2-mediated cleavage of focal contacts. This protease is activated by EGF-induced MAPK (mitogen-activated protein kinase) and promotes the migration and invasion of tumor cells. There appears to be a correlation between FAK overexpression in tumors and their invasive … porsche boardwalkWeb學術名詞. 點狀黏著. focal adhesion. 焦點附著複合體. focal adhesion complex. 暫無建議訊息. Copyright © 2012國家教育研究院 版權所有 建議最佳瀏覽螢幕解析度1024×768. 三 … iris hooks cataract surgery cptWebFocal adhesions are integrin-containing, multi-protein structures that form mechanical links between intracellular actin bundles and the extracellular matrix or substrate in many cell … porsche bethesda servicehttp://cjbmb.bjmu.edu.cn/CN/Y2016/V32/I10/1091 porsche boardwalk dallas