WebFeb 1, 1991 · Outcome-adaptive randomization (OAR) has been proposed as a corrective to certain ethical difficulties inherent in the traditional randomized clinical trial (RCT) using … WebFeb 1, 1987 · Randomized clinical trials pose a number of fundamental ethical problems to which morally sensitive investigators must give careful consideration. The randomized …
The ethics of randomized clinical trials - PubMed
WebApr 11, 2024 · This study has been approved by the ethics committee of Beijing Luhe Hospital, Capital Medical University, Beijing, China and registered at ... et al. (2024). Adjuvant high-flow normobaric oxygen after mechanical Thrombectomy for anterior circulation stroke: a randomized clinical trial. Neurotherapeutics 18, 1188–1197. doi: … WebFeb 1, 1987 · Abstract. Randomized clinical trials pose a number of fundamental ethical problems to which morally sensitive investigators must give careful consideration. The … the art of scientific storytelling
Frontiers Vertebrobasilar artery cooling infusion in acute ischemic ...
Web1 day ago · The trial was conducted in accordance with the principles of the Declaration of Helsinki and Good Clinical Practice. Regulatory approval was granted by the UK Medicines and Healthcare Products Regulatory Agency (CTA 21584/0438/001–0001) and ethics approval by NHS East of England–Cambridge East Research Ethics Committee. WebSep 15, 2024 · In this paper, we discuss two major ethical dilemmas: (1) the equipoise of continuing new vaccine trials in the advent of successful candidates and (2) the maleficence of blinded placebo arms. WebNov 1, 2024 · Conclusions and relevance: In these 2 randomized clinical trials, financial incentives increased trial enrollment in 1 of 2 trials and did not produce undue or unjust inducement or other unintended consequences in either trial. Trial registration: ClinicalTrials.gov Identifier: NCT02697799 . Publication types Randomized Controlled Trial the glass as half full