Dynein light intermediate chain
WebOct 1, 2014 · The LIC domain structure has interesting parallels with the dynein intermediate chain, which has a well-ordered WD repeat domain that interacts with the heavy chain and a less conserved disordered … WebDynein Light Intermediate Chains as pivotal determinants of dynein multifunctionality. Journal of Cell Science May 18, 2024 The exocyst …
Dynein light intermediate chain
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WebAug 1, 2011 · The light chain composition of chicken brain myosin-Va: calmodulin, myosin-II essential light chains, and 8-kDa dynein light chain/PIN. Cell Motil Cytoskeleton. … WebJul 21, 2004 · Intraflagellar transport (IFT), the bidirectional movement of particles along flagella, is essential for flagellar assembly. The motor for retrograde IFT in Chlamydomonas is cytoplasmic dynein 1b, which …
WebJun 12, 2007 · The dynein light chains (LCs) LC8 and TcTex1 form a subcomplex with dynein intermediate chains, and they also interact with numerous protein and ribonucleoprotein partners. This observation has led to the hypothesis that these subunits serve to tether cargo to the dynein motor. WebMar 27, 2024 · Introduction. Cytoplasmic dynein 1 (dynein) is a microtubule (MT) motor protein complex that is responsible for retrograde transport of cellular cargos such as proteins, RNAs, and organelles 1, 2.Dynein is composed of four subunit classes: the heavy chain (HC), light intermediate chain (LIC), intermediate chain (IC), and light chain …
WebMar 4, 2024 · Coil: yellow. Ribbons are thickened and non-physical struts added to make more robust for 3D printing. 6f1y-ribbon-rainbow-vis. Molecular ribbon representation with each biopolymer chain colored by rainbow from N-terminus (red) to C-terminus (blue). Intended for visualization only, not 3D printing. WebJan 1, 2024 · Originally, the ability of the dynein motor complex to tether and transport numerous cargo was ascribed to the dynein light chains—relatively small, homodimeric …
WebJun 1, 2002 · Light intermediate chain of the cytoplasmic dynein complex 2, a multisubunit complex composed at least of eleven different proteins. The cytoplasmic …
WebMay 1, 2024 · In some cases, dynein-cargo associations are mediated directly by the cytoplasmic dynein intermediate or light intermediate chain subunits [[2], [3], [4]]. Alternatively, dynein can interact with cargoes through either of two regulatory complexes, dynactin and Nde1-LIS1, which, respectively, in turn, control transport processivity [ 5 , 6 … how many sports are in the ncaaWebAug 8, 2024 · An analysis of dynein-2 subunit interactions via a visible immunoprecipitation (VIP) assay has been published, demonstrating interactions between WDR60 and TCTEX1/3-TCTEX1D2; WDR34 and LC8 and Roadblock; and the intermediate chain-light chain complex with the heavy chain and light-intermediate chain . how many sports betting shops in zimbabweWebJan 7, 2024 · Dynein is a 12-subunit complex consisting of a dimerized heavy chain (HC) with a C-terminal motor domain and two copies each of five accessory chains that bind … how many sports are in a heptathlonWebDec 23, 2016 · Dynein is a large, non-covalent cytoplasmic complex of protein subunits including heavy chains, intermediate chains, light … how did sinema vote todayWebNov 23, 2024 · Central to the function of this motor protein complex is dynein intermediate chain (IC), which binds the three dimeric dynein light chains at multivalent sites, and dynactin p150 Glued and nuclear distribution protein (NudE) at overlapping sites of its intrinsically disordered N-terminal domain. The disorder in IC has hindered cryo-electron ... how many sports are in the winter olympicsWebSep 26, 2024 · Dynein-associated light and intermediate chains regulate the biophysical mechanisms of axonemal dynein. Tctex-type outer arm dynein light chain 2 (LC2) regulates flagellar bending wave propagation direction, amplitude, and frequency in Chlamydomonas reinhardtii. However, the role of Tctex-type light chains in regulating T. how did singapore become independentWebDynein axonemal intermediate chain 1 is a protein that in humans is encoded by the DNAI1 gene. ... The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. This gene encodes an intermediate chain dynein, belonging to the large family of motor ... how many sports can i follow on flashscore