Dexd/h-box helicase 58
WebNCBI Full Gene Name DExD/H-box helicase 58; NCBI Gene Aliases RIG-I, RIG1, RIGI, RLR-1, SGMRT2; Clonality Monoclonal; Antibody Type Primary Antibodies; Specifications/Features Available conjugates: Alexa Fluor 594. Add to Compare List. Novus Biologicals. United States: 10771 E Easter Ave WebThe IUPHAR/BPS Guide to Pharmacology. DExD/H-box helicase 58 - RIG-I-like receptor family. Detailed annotation on the structure, function, physiology, pharmacology and …
Dexd/h-box helicase 58
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WebThis website you visit will use cookies in order to improve your user experience by enabling that website to ‘remember’ you. Should you continue navigating we will consider that you accept their use. WebOct 26, 2008 · RIG-I and Mda5 consist of two amino-terminal caspase-recruitment domains, a DExD/H-box RNA helicase domain and a carboxy-terminal repressor domain, whereas LGP2 lacks a caspase-recruitment domain.
Web暨南大学,数字图书馆. 开馆时间:周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆 WebNov 26, 2024 · MDA5 contains two domains, the DExD/H-box RNA helicase and a C-terminal domain, that are required for RNA binding . In addition, there are two N-terminal caspase activation and recruitment domains ... :644–58. Taniguchi T, Ogasawara K, Takaoka A, Tanaka N. IRF family of transcription factors as regulators of host defense. ...
WebAug 9, 2016 · RNA helicases are involved in almost every aspect of RNA, from transcription to RNA decay. DExD/H-box helicases comprise the largest SF2 helicase superfamily, which are characterized by two conserved RecA-like domains. In recent years, an increasing number of unexpected functions of these proteins have been discovered. They play … WebSep 22, 2024 · Predicted to enable several functions, including ATP binding activity; DNA binding activity; and helicase activity. Involved in RNA interference. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome. Orthologous to human DDX58 (DExD/H-box helicase 58); DHX58 (DExH-box helicase …
WebMar 22, 2024 · Sertoli cell -only syndrome (SCOS) is a type of testicular pathological failure that causes male infertility and no effective treatment strategy, is available for this condition. Moreover, the molecular mechanism underlying its development remains unknown. We identified DExD/H-Box helicase 58 (DDX58) as a key gene in SCOS based on four …
WebAug 25, 2006 · INTRODUCTION. The DExD/H box family of proteins is distinguished by the presence of several conserved motifs, which include the characteristic ‘DExD/H’ … only remembered ira d. sankeyWebRNA helicases of the DEAD box and related DExD/H proteins form a very large superfamily of proteins conserved from bacteria and viruses to humans. They have seven to eight conserved motifs, the characteristics … only remembered lyricsWebGene ID: 103821258, updated on 5-Oct-2024. Summary Other designations. antiviral innate immune response receptor RIG-I, DExD/H-box helicase 58, DExD/H-box helicase 58 only relevant values tableau not showingWebNov 2, 2024 · DExD/H-box RNA helicases are categorized as members of the helicase superfamily II by virtue of their conserved motif DExD/H amino acid signature sequence, which represents the core domain at which NTP binding and hydrolysis occur. ... 58. Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 144(5), … inweld catalogWebOct 23, 2024 · DExD/H-box helicase 36 (DHX36) is known to be an ATP-dependent RNA helicase that unwinds the guanine-quadruplexes DNA or RNA, but emerging data suggest that it also functions as pattern recognition receptor in innate immunity. Porcine reproductive and respiratory syndrome virus (PRRSV) is an Arterivirus that has been devastating the … only remind me of you chordsWebDExD (DDX)- and DExH (DHX)-box RNA helicases, named after their Asp-Glu-x-Asp/His motifs, are integral to almost all RNA metabolic processes in eukaryotic cells. They play myriad roles in processes ranging from transcription and mRNA-protein complex remodeling, to RNA decay and translation. This last facet, translation, is an intricate … inweld certificatesWebOct 22, 2008 · They also cloned human LGP2. Both proteins contain 678 amino acids and have a DEAD/H box domain and a C-terminal helicase domain. The DEAD/H box domain contains a conserved ATP-binding motif, an ATPase motif, and an unwinding motif, and the helicase domain contains an RNA-binding motif. Mouse and human LGP2 share 79% … in welcoming you