WebThe first CtBP homologue (CtBP1) was identified as a binding partner for the adenoviral transforming protein E1A 6 however CtBP homologues have been implicated as cofactors for a number of cellular transcriptional … WebApr 10, 1998 · This protein, designated the CtBP-interacting protein, CtIP (CtBP-interacting protein) is characterized here. To confirm that CtIP could directly bind with …
Acetylation of adenovirus E1A regulates binding of the ... - PNAS
WebOct 23, 2024 · Abstract Human C-terminal binding protein (CtBP)-interacting protein (CtIP) is a central regulator to initiate DNA end resection and homologous recombination (HR). Several studies have shown that post-translational modifications control the activity or expression of CtIP. WebMay 1, 2024 · Typical for multivalent adaptor proteins, CtIP contains various short linear sequence motifs facilitating interactions between protein-binding partners, some of which are governed by CtIP phosphorylation (Fig. 1) [2, 24].For instance, CDK-mediated phosphorylation of CtIP at S327 is a prerequisite for the binding of BRCA1 BRCT … port orford cedar 1x6
Zeb1 promotes corneal neovascularization by regulation of
WebDec 12, 2000 · The amino terminus of E1A binds to CBP/p300 and associated histone acetyltransferases such as P/CAF. The carboxyl terminus binds to the carboxyl-terminal … WebJan 30, 2006 · Most of the factors that interact with CtBP are transcriptional regulators and bind to CtBP through a conserved Pro-X-Asp-Leu-Ser (“PXDLS”) CtBP-binding domain that is necessary and probably sufficient for the interaction (11, 12).It has recently been shown that CtBP-containing protein complexes include several factors that coordinate … WebJul 28, 2000 · The results indicate that E1a's interaction with CtBP activates at least three epithelial cell adhesion gene promoters. The E-cadherin repressor appeared to be the CtBP-interacting protein δ EF1 ... iron mountain small business huntsville al